The magnesium dependence of sodium-pump-mediated sodium-potassium and sodium-sodium exchange in intact human red cells
نویسندگان
چکیده
منابع مشابه
Sodium pump-mediated ATP:ADP exchange. The sided effects of sodium and potassium ions
Resealed human red cell ghosts containing caged ATP (Kaplan et al., 1978) and [3H]ADP were irradiated at 340 nm. The photochemical release of free ATP initiated a rapid transphosphorylation reaction (ATP:ADP exchange), a component of which is inhibited by ouabain. The reaction rate was measured by following the rate of appearance of [3H]ATP. The sodium pump-mediated ATP:ADP exchange reaction sh...
متن کاملSodium, cell sodium and sodium pump changes in PE
1. Abstract 2. Introduction 3. Sodium Regulation in Uncomplicated Pregnancy 4. Sodium Regulation in Preeclampsia 5. Cell Sodium Regulation in Uncomplicated Pregnancy 5.1. Cell Sodium and Cell (Na,K)ATPase or Sodium Pump (SP) in Uncomplicated Pregnancy 5.2. Other Cell Sodium Transport Systems in Uncomplicated Pregnancy 6. Cell Sodium Regulation in Preeclampsia 6.1. Cell Sodium and Potassium in P...
متن کاملSodium channel, sodium pump, and sodium-calcium exchange activities in synaptosomal plasma membrane vesicles.
Two mechanisms of Na+ influx have been observed using synaptosomal plasma membrane vesicles purified by density gradient centrifugation from a synaptosomal hypotonic lysate. First, a 5-fold increase in uptake over basal Na+ entry occurs with 50 microM veratridine. The veratridine-dependent Na+ uptake is partially inhibited by 2 microM tetrodotoxin with an apparent time dependency of action (hal...
متن کاملReduced sodium concentration and increased sodium-potassium pump activity of erythrocytes in human hypertension.
Erythrocyte Nai, Nai/Ki and ouabain-sensitive and ouabain-insensitive 86Rb uptake (K transport) were measured in whole blood of 16 normotensive and 19 hypertensive white male subjects, within seconds or minutes after withdrawal of blood. Erythrocyte Nai and Nai/Ki were reduced (p less than 0.05), and ouabain-sensitive 86Rb uptake was increased (p less than 0.01) in hypertensive subjects. In a s...
متن کاملSodium and potassium fluxes and membrane potential of human neutrophils: evidence for an electrogenic sodium pump
Sodium and potassium ion contents and fluxes of isolated resting human peripheral polymorphonuclear leukocytes were measured. In cells kept at 37 degrees C, [Na]i was 25 mM and [K]i was 120 mM; both ions were completely exchangeable with extracellular isotopes. One-way Na and K fluxes, measured with 22Na and 42K, were all approximately 0.9 meq/liter cell water . min. Ouabain had no effect on Na...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1981
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1981.sp013756